#cardiac

As always when introduced to a character I've never read in earnest, I open up the floor to opinions from others.

Developing a Heart

During embryo development 'making' a heart requires a fine balance of factors stimulating or suppressing different cell types at the right time in the right place. This study in zebrafish defines the equilibrium required of two transcription factors, Nr2f1a and Isl1, to correctly drive differentiation from progenitor cells and maintain the identities of three heart cell types – pacemaker cardiomyocytes, atrial cardiomyocytes and epicardial cells

Read the published research article here

Image from work by Kendall E. Martin and colleagues

Molecular Cardiovascular Biology Division and Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Development, June 2026