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Lisocabtagene maraleucel
Lisocabtagene maraleucel (liso-cel; JCAR017; Anti-CD19 CAR T-Cells) is an investigational chimeric antigen receptor (CAR) T-cell therapy designed to target CD19, [1][2] which is a surface glycoprotein expressed during normal B-cell development and maintained following malignant transformation of B cells. [3][4][5] Liso-cel CAR T-cells aim to target and CD-19 expressing cells through a CAR…
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Breyanzi approved for certain types of large B-cell lymphoma
Breyanzi approved for certain types of large B-cell lymphoma
Cell-based gene therapy Breyanzi (lisocabtagene maraleucel) has been approved to treat adults with certain types of large B-cell lymphoma who have not responded to other systemic treatment, the U.S. Food and Drug Administration announced Friday. The chimeric antigen receptor T cell therapy was approved for relapsed or refractory large B-cell lymphoma, including diffuse large B-cell lymphoma,…
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