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Boceprevir
Boceprevir Brand Names: U.S. Victrelis™ Brand Names: Canada Victrelis™ Pharmacologic Category Antiviral Agent; Protease Inhibitor Dosing: AdultTreatment of chronic hepatitis C (CHC): Oral: 800 mg 3 times/day (in combination with peginterferon alfa and ribavirin) Treatment-naive patients (interferon-responsive at week 4): Weeks 1-4: Peginterferon alfa with concomitant ribavirin only Weeks 5-8:…
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Boceprevir, Боцепревир ,بوسيبريفير , 波普瑞韦
Boceprevir, Боцепревир ,بوسيبريفير , 波普瑞韦
BOCEPREVIR 110-120 °C Handelsname: Victrelis®, Patentnummer: WO2002008244 CAS394730-60-0 Schering CorporationN-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-{N-[(tert-butylamino)carbonyl]-3-methyl-L-valyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide Hepatitis C virus (HCV) chronically infects more than 200 million people worldwide, and current treatment options have been very…
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BOCEPREVIR
BOCEPREVIR 110-120 °C Handelsname: Victrelis®, Patentnummer: WO2002008244 CAS394730-60-0 Schering Corporation N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-{N-[(tert-butylamino)carbonyl]-3-methyl-L-valyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide Hepatitis C virus (HCV) chronically infects more than 200 million people worldwide, and current treatment options have been very…
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Day 14-15 - May 23, 2014
Long Term Care
I worked with Dr. Fox (Pharmacist) and Courtney (Resident Pharmacist) in long term care. I mostly worked with Courtney to evaluate anticoag patients' INRs. We looked through patient cases and altered their warfarin doses as needed.
Good Shepherd's Free Clinic
After we were done at the hospital, Kathryn and I volunteered at Good Shepherd's Free Clinic. It is a small clinic located at the old YMCA in Salisbury. It is only open on Thursdays and runs solely on donations from the community. Ted, the primary care clinical pharmacist volunteers here every Thursday, so we decided to join him! The clinic has a surprisingly large pharmacy, fully stocked on almost any medication you can think of (except for controlled substances). While waiting for the pharmacy to open, I helped the nurses perform vitals on their patients including checking a patient's blood glucose level. We then stayed primarily in the pharmacy to fill prescriptions that came our way. Lori (a pharmacy student at UNC) also came with her preceptor, Steve (of Innes St Pharmacy). Ted was constantly quizzing us on drug facts, so that kept us on our toes while working. Overall it was a great experience!
Infectious Disease
Courtney (PharmD from Wingate) is the current infectious disease (ID) clinical pharmacist in the clinic. She actually is one of two clinical pharmacists in Home Based Primary care. In October, the current ID pharmacist left, so Courtney has been filling in since then. Good news though, a new ID pharmacist will be coming in within the next month. Everyone is very excited for that! The day started with a meeting with us, the ID physicians and nurses. Here, they discussed patients who are eligible to receive Hepatitis C (HCV) treatment. Previously, the common treatment for a HCV patient would be peginterferon alfa-2a, an anti-viral (simeprevir, boceprevir) and ribavirin. A new medication, Sofosbuvir, came into the market in December of 2013. This drug has a very high cure rate, and is very expensive (Upwards of $80,000 for a three month treatment, in addition to the cost off the other medications). Keep in mind that the VA essentially pays for everything. Because of this, it is important to properly screen and evaluate patients who are eligible and ready to begin this treatment. They went through patient cases, evaluating factors such as if it was their first treatment, if not, then if they relapsed/reached futility, and from what treatment regimen, NS3 test results (for mutations), what genotype of Hepatitis C they are, if they have co-morbidities (other disease states), and presence of mutations. The rest of the day consisted of us meeting with patients regarding their current treatment regimen. We also got to tell a patient he is cured of Hepatitis C!
Epatite C, il futuro è già qui: da Londra nuove conferme su efficacia e sicurezza della triplice terapia
Epatite C, il futuro è già qui: da Londra nuove conferme su efficacia e sicurezza della triplice terapia
Nella terapia dell’Epatite C il futuro è adesso grazie alle terapie innovative già disponibili, entrate stabilmente nella pratica clinica, con conferme crescenti di efficacia e sicurezza, e gestibili dal sistema sanitario anche sotto il profilo economico: in particolare la “triplice” terapia è, oggi, quella che meglio garantisce elevata efficacia, tollerabilità, costi contenuti e sostenibilità…
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Hepatite C - grandes esperanças com o Sofosbuvir
Um comitê de experts da FDA, o órgão controlador de medicamentos norte-americano e que serve como…
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Hepatite C - nova terapia com simeprevir
Um comitê de experts do poderoso FDA, órgão regulador de medicamentos norte-americano, recomendou…
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Novo Artigo em Soropositivo.Org
Um Novo Artigo foi Publicado em http://soropositivo.net.br/hiv-aids-hpv-hepatite/novos-medicamentos-para-hepatite-c.html
Novos medicamentos para hepatite C
Doença, Hepatite C, é responsável por 70% dos casos crônicos, 40% dos casos de cirrose e é a primeira causa de transplantes de fígado no mundo Os medicamentos boceprevir e telaprevir, considerados os mais modernos para tratamento da...
