#anthelmintic

Helminth infections, particularly Ascaridia galli, significantly impair poultry health and productivity, especially among native chickens raised under natural conditions. The continuous of use of synthetic anthelmintics have led to resistance and drug residue concerns, emphasizing the need for natural alternatives. This study aimed to evaluate the in vitro anthelmintic activity of jackfruit (Artocarpus heterophyllus) seed ethanolic extract against Ascaridia galli and compare its efficacy with albendazole. A Completely Randomized Design (CRD) was employed with six treatments, 3 concentrations of albendazole (25, 50 and 100mg/5ml of distilled water) and 3 concentrations of jackfruit seed ethanolic extract (25, 50 and 100μl/5ml distilled water) replicated three times. Adult Ascaridia galli worms were exposed to each treatment, and observations on paralysis and mortality were recorded every 30 minutes. Paralysis was occurred as early as 1:30 hours with complete mortality recorded at 3 hours. The 100mg albendazole and 100μl of jackfruit seed ethanolic extract treatments showed the highest mortality, while 25μl jackfruit seed ethanolic extract exhibited comparable activity to 25mg albendazole, yielding significant paralysis (3.67) and mortality (5.67 values). Results indicate that jackfruit seed ethanolic extract possesses potent, rapid and dose dependent anthelmintic activity against Ascaridia galli. The 25μl/5ml of distilled water concentration was identified as minimal effective and potentially safe dose. Therefore, jackfruit seed ethanolic extract represent a promising, affordable, and ecofriendly natural deworming alternative for sustainable poultry production.

Parasites pose a significant threat to the health of small ruminants. Natural products such as Adlai roots have anthelmintic potentials. The study aimed to determine the Anthelmintic potential to the small ruminants. A total of 12 goats and sheep regardless of sex and age were used in the study and randomly distributed into four (4) Treatments with Three (3) replications following Randomized Complete Block Design. There were four different levels of Treatments. Treatment 1 as the control, Treatment 2 (100ml of Adlai roots decoction), Treatment 3 (150ml of Adlai roots decoction), and Treatment 4 (200ml of Adlai roots decoction). Freshly excreted feces were collected and placed in plastic cups and immediately examined through Modified Mc Master Test to evaluate the Anthelmintic activity of the designated treatments. The evaluation criteria were based on the frequency counts of egg parasites and oocysts per 2 grams of feces under different treatments. Results were analyzed using the analysis of variance (ANOVA) of Randomized Complete Block Design (RCBD). Tukey’s test was used to compare treatment means showing significant difference. Statistical results were non-significant among Treatment means in all of the parameters except for the strongylid counts for the month of April which showed significant difference among treatment mean at (P< 0.05) where sheep treated with Treatment 4 (200ml of Adlai roots decoction). Adlai roots decoction has anti-parasitic activity.

Parasites pose a significant threat to the health of small ruminants. Natural products such as Adlai roots have anthelmintic potentials. The study aimed to determine the Anthelmintic potential to the small ruminants. A total of 12 goats and sheep regardless of sex and age were used in the study and randomly distributed into four (4) Treatments with Three (3) replications following Randomized Complete Block Design. There were four different levels of Treatments. Treatment 1 as the control, Treatment 2 (100ml of Adlai roots decoction), Treatment 3 (150ml of Adlai roots decoction), and Treatment 4 (200ml of Adlai roots decoction). Freshly excreted feces were collected and placed in plastic cups and immediately examined through Modified Mc Master Test to evaluate the Anthelmintic activity of the designated treatments. The evaluation criteria were based on the frequency counts of egg parasites and oocysts per 2 grams of feces under different treatments. Results were analyzed using the analysis of variance (ANOVA) of Randomized Complete Block Design (RCBD). Tukey’s test was used to compare treatment means showing significant difference. Statistical results were non-significant among Treatment means in all of the parameters except for the strongylid counts for the month of April which showed significant difference among treatment mean at (P< 0.05) where sheep treated with Treatment 4 (200ml of Adlai roots decoction). Adlai roots decoction has anti-parasitic activity.

Parasitic infestation, particularly Ascaridia galli, significantly threatens poultry production, reducing growth and productivity. A. galli, a nematode that frequently affects chickens, can be treated with a synthetic anthelmintic; however, resistance to commercial dewormers has developed, which can cause harm to poultry. These problems catch the interest of many researchers who are driven to establish plant-based products to minimize costs. This study examines the potential anthelmintic properties of papaya seeds administered to broiler chickens at varying doses. The experiment was patterned in a Complete Randomized Design in which four treatments were observed and replicated into three, with five experimental birds in each treatment: T1- (Control), T2-(1mg PPS/bird), T3-(1.5mg PPS/bird), and T4-(2mg PPS/birds). Treatment 4, with the highest inclusion rate, has shown an excellent result, indicating that powdered papaya seed at this amount can be used as an alternative to commercial dewormers. In comparison, Treatment 3, with an amount of 1.5 mg, yields comparable results to the commercial dewormer. However, powdered papaya seed given in a lower amount yields a poorer result compared to other treatments. The findings in this study indicate that Carica papaya seed exhibits significant results against A. galli. Future studies should conduct sensory evaluations to assess the effects on the meat of broiler chickens, as well as evisceration activity, to verify the presence of gastrointestinal parasites in the gastrointestinal tract.