#anandamide

There are many secrets surrounding the functioning of the human body that we might have never understood if it weren’t for the cannabis plant. One of them is anandamide, one of the pieces of the puzzle collected over the last few decades which demonstrates that marijuana is a therapeutic miracle capable of bringing happiness into our lives.

Anandamide is a natural cannabinoid produced by the human body that gets its name from the Sanskrit word ‘ananda’, which means joy, bliss, and delight (hence why it is also known as ‘the bliss molecule’). This almost unknown compound, which is present in all humans, plays an important role in the regulation of our emotional state. In addition, it also plays a part in our eating patterns and in pain relief, although its main function is to help make us happy and healthy.

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Active ingredients in both hot peppers and cannabis calm the gut's immune system

You wouldn't think chili peppers and marijuana have much in common. But when eaten, both interact with the same receptor in our stomachs, according to a paper by UConn researchers published in the April 24 issue of the journal Proceedings of the National Academy of Sciences. The research could lead to new therapies for diabetes and colitis, and opens up intriguing questions about the relationship between the immune system, the gut and the brain.                                

Touch a chili pepper to your mouth and you feel heat. And biochemically, you aren't wrong. The capsaicin chemical in the pepper binds to a receptor that triggers a nerve that fires off to your brain: hot! Those same receptors are found throughout the gastrointestinal tract, for reasons that have been mysterious.

Curious, UConn researchers fed capsaicin to mice, and found the mice fed with the spice had less inflammation in their guts. The researchers actually cured mice with Type 1 diabetes by feeding them chili pepper. When they looked carefully at what was happening at a molecular level, the researchers saw that the capsaicin was binding to a receptor called TRPV1, which is found on specialized cells throughout the gastrointestinal tract. When capsaicin binds to it, TRPV1 causes cells to make anandamide. Anandamide is a compound chemically akin to the cannabinoids in marijuana. It was the anandamide that caused the immune system to calm down. And the researchers found they could get the same gut-calming results by feeding the mice anandamide directly.

Chocolate contains the compound anandamide, which actually stimulates the human brain the same way as marijuana. source

Ton cerveau possède une pharmacie complète, capable de synthétiser des antidouleurs vingt fois plus puissants que la morphine. Mais cette pharmacie reste fermée si tu n’as pas les clés. Je me souviens des deux premiers moments dans ma vie où j’ai ressenti une libération d’endorphines avec un état d’invincibilité. La première fois, c’était à l’école primaire pendant un cours de sport. On devait…

How to Get High Naturally: 9 Drug-Free Ways to Boost Your Mood

Can you really get high naturally without using drugs or alcohol? Absolutely. Your body is a powerful pharmacy capable of producing euphoric states on its own—no substances needed.Activities like running, breathing exercises, and spending time in nature release feel-good chemicals such as dopamine, serotonin, endorphins, and anandamide. These natural highs are legal, sustainable, and deeply fulfilling, without the crash or addiction risk.

What Is a Natural High?

Getting high usually means chemically altering consciousness through synthetic substances or plant-based compounds like cannabis to achieve euphoria, relaxation, or heightened sociability.Cannabis produces over 500 unique secondary metabolites, with over 100 classified as cannabinoids. THC (tetrahydrocannabinol), the most famous, binds to CB1 receptors in the brain, triggering a dopamine surge and serotonin modulation. This produces bliss, creativity, and relaxation.Here’s the fascinating part: THC mimics anandamide, the body’s own “bliss molecule.” Anandamide, from the Sanskrit ananda, meaning joy, regulates mood, motivation, and emotional balance naturally.But cannabis is just one example. Plants like Echinacea also contain compounds that bind to the endocannabinoid system (ECS), showing nature’s vast influence on mental states.

Natural Highs vs Drug Highs

Drug-induced highs, from THC to MDMA or alcohol, deliver intense neurotransmitter spikes followed by crashes, dependency, or harm. They override your natural systems.Natural highs work with your body. They stimulate brain systems gradually, creating subtler but longer-lasting euphoria, promoting resilience and holistic wellness.

9 Natural Ways to Get High Naturally Without Drugs

Ready to experience a high that’s sustainable, safe, and rooted in your biology? Here are nine science-backed, drug-free ways to feel amazing—naturally.1. Music: Press Play for a Dopamine RushMusic hits deeper than words—it’s a drugless dopamine rush you can summon anytime. Carefully arranged sound frequencies stimulate the brain’s reward pathways, much like drugs—but without the downside.Those goosebumps during your favorite song? That’s dopamine surging through your system. Studies confirm music reduces anxiety, lowers blood pressure, and elevates mood.Whether dancing, singing, or simply listening with eyes closed, music offers a powerful, accessible natural high.2. Breathing Exercises: Your Consciousness, ControlledYour breath acts like a remote control for both your nervous system and consciousness. Drawing from ancient traditions like yoga and tai chi, modern techniques, such as the Wim Hof Method and holotropic breathing, tap into this transformative power.Holotropic breathing, in particular, can unlock deep emotional release, ease fears around death, and enhance self-awareness. Some practitioners even describe the experience as psychedelic-like, despite involving no substances.By practicing conscious breathwork, you can shift brain chemistry, calm the nervous system, and achieve euphoric, transcendent states—all from within yourself.3. Running: Tap Into an Ancient EuphoriaOur ancestors evolved as endurance runners, using persistence hunting to survive. Running remains hardwired in our biology, rewarding us with the "runner’s high."Science reveals this high stems from endogenous opioids (natural painkillers) and anandamide—the “bliss molecule” that binds CB1 receptors much like THC, producing joy and calm.A simple jog—through a forest, park, or neighborhood—activates this ancient system of natural euphoria.

4. Gardening: Get Your Hands Dirty, Get HappyGardening isn’t just about tending plants—it’s about connecting with the rich soil beneath them. Healthy soil hosts a microbial universe, including Mycobacterium vaccae, a bacterium that boosts serotonin production.Digging in soil exposes you to this microbe, which lowers inflammation, regulates immunity, and alleviates stress, creating a mild, blissful natural high.Gardening is a grounded, sensory-rich ritual that nurtures your inner well-being one handful of soil at a time.5. Forest Bathing: Breathe in Nature’s BlissTerpenes, the aromatic compounds that give cannabis its distinctive scents, are abundant throughout nature, with over 30,000 types found in plants, fungi, and even some animals.Forest bathing, a mindful walk through wooded areas, immerses you in terpene-rich air. Pine forests release α-pinene and β-pinene, which reduce inflammation, boost memory, and enhance mood.This serene practice offers a powerful path to mental clarity and emotional uplift—a deeply restorative natural high.6. Earthing: Barefoot and GroundedModern life insulates us from Earth’s natural electric charge. Yet your body evolved in constant contact with the ground’s electromagnetic field.Earthing—walking barefoot on grass, soil, or sand—allows your body to absorb the Earth’s electrons. This reduces inflammation, lowers stress hormones, improves sleep, and stabilizes internal rhythms.Earthing reconnects you with your environment, offering a calming, restorative natural high.

7. Chocolate and Black Truffles: Edible BlissBlack truffles (Tuber melanosporum) are more than a culinary delicacy—they produce enzymes that create anandamide, the brain’s bliss molecule. Every shave onto your pasta subtly elevates your mood.Dark chocolate doesn’t contain anandamide but has compounds that block FAAH, the enzyme that breaks down anandamide. This lets your body retain more bliss-inducing chemicals longer.Together, truffles and chocolate offer delicious, drug-free mood boosts.8. Sex and Love: The Ultimate Natural HighSex and love profoundly alter brain chemistry, offering some of the strongest natural highs.Sex releases dopamine and anandamide during exertion, followed by a surge of oxytocin—the bonding hormone—that promotes relaxation, trust, and connection.Love begins with attraction fueled by testosterone, estrogen, and dopamine, evolving into deep attachment through oxytocin and vasopressin.Together, sex and love create a powerful, sustainable euphoria that supports mental health, emotional resilience, and stress relief.9. Combining Methods for Maximum EffectFor the most intense natural high, try stacking these activities:- Run through a leafy park with your favorite playlist (endorphins + forest bathing + dopamine). - Stretch barefoot in the grass (earthing). - Savor a piece of dark chocolate (anandamide boost). - Finish with slow, deep breathing to extend euphoria.This combo blends physical, emotional, and chemical wellness into one uplifting ritual.

Quick Summary:

MethodKey Chemical / EffectWhy It Feels GoodMusicDopamineEmotional highs, chillsBreathing ExercisesOxygen + CO₂ regulationTranquility, altered consciousnessRunningAnandamide, EndorphinsNatural euphoria, anxiety reliefGardeningSerotonin via microbesMood boost from soil bacteriaForest BathingTerpenesClarity, memory boostEarthingElectron transferAnti-inflammatory, calmingChocolate & TrufflesFAAH inhibitors, AnandamideSustains bliss chemicals, cannabis-likeSex & LoveOxytocin, DopamineConnection and pleasureStacking MethodsCombinationAmplified, sustained natural high

Unlock Natural Euphoria: A Healthier Way to Feel High

You don’t need substances to feel euphoric, connected, or spiritually awake. From extreme sports to gentle walks in nature, the world offers countless ways to elevate your state of being.Whether you're seeking everyday joy or navigating addiction recovery, tapping into your body’s natural chemistry provides lasting benefits without side effects or stigma.Nature, movement, love, and breath are your birthright. You were made to feel amazing, naturally.

Frequently Asked Questions (FAQs) about How to Get High Naturally Without Drugs or Alcohol