NIPT vs Amniocentesis vs CVS: Accuracy, Risk & When You Actually Need Them
Prenatal testing has become more advanced, offering multiple options to detect genetic and chromosomal conditions during pregnancy. Among the most commonly recommended tests are NIPT, Amniocentesis, and CVS. While all three are used to assess fetal health, they differ significantly in terms of accuracy, risk, and timing.
Choosing the right test depends on individual risk factors, medical history, and previous screening results. For reliable and advanced diagnostics, you can explore comprehensive fetal imaging services that include both screening and diagnostic procedures.
What Is NIPT (Non-Invasive Prenatal Testing)?
NIPT is a screening test that analyzes small fragments of fetal DNA present in the mother’s blood.
Can be done from 10 weeks of pregnancy
Highly accurate for detecting conditions like Down syndrome
Completely non-invasive and safe
Around 99% for common chromosomal abnormalities
Still considered a screening test, not diagnostic
What Is CVS (Chorionic Villus Sampling)?
CVS is a diagnostic test that involves taking a small sample of placental tissue.
Usually performed between 11–13 weeks
Provides definitive results for genetic conditions
Nearly 100% diagnostic accuracy
Small risk of miscarriage (slightly higher than amniocentesis in some cases)
Amniocentesis is another diagnostic test that involves collecting amniotic fluid from around the baby.
Typically done after 15 weeks
Used to confirm chromosomal abnormalities
Nearly 100% diagnostic accuracy
Small risk of miscarriage
Generally considered slightly safer than CVS
When Do You Actually Need These Tests?
Not every pregnancy requires all three tests.
You may consider NIPT if:
You want early, non-invasive screening
You are above 30–35 years of age
There is moderate risk based on initial scans
You may need CVS or Amniocentesis if:
NIPT or NT scan shows high risk
There is a family history of genetic disorders
Previous pregnancy had abnormalities
In such cases, decision-making should always be guided by an experienced professional. You can review the expertise of a fetal medicine specialist before proceeding with any diagnostic test.
There is no single “best” test—it depends on the situation.
Low risk → NIPT is usually sufficient
High risk or abnormal screening → Diagnostic tests (CVS or Amniocentesis) are recommended
Need early confirmation → CVS
Safer confirmation later → Amniocentesis
NIPT, CVS, and Amniocentesis each serve a different purpose in prenatal care. The key is to choose the right test based on your medical condition rather than opting for unnecessary procedures.
If you are unsure about which test is appropriate, seeking expert guidance is essential. You can book your appointment to get personalized advice and accurate diagnosis.
